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P-II trial, conducted by Belenos’partner Keymed Biosciences, assessed BEL512 (SC; 300mg, Q12W/Q24W or 600mg, Q24W) vs PBO, both on top of intranasal corticosteroid (QD), in 120 Chinese pts with CRSwNP with NPS of ≥5 (≥2 polyps/nostril) & a NCS of 2-3
Trial met its 1 & 2EPs, with the BEL512 showing statistically significant improvements at Wk. 24. Benefits emerged by WK. 4 & were sustained throughout the treatment & follow-up periods; data to be presented & published in the futureÂ
Durable activity support 6mos. dosing, with Keymed planning to initiate a P-III study in China soon, while Belenos will begin a P-III study outside China in H1’27
Ref: Businesswire | Image: Belenos | Press Release
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The post Belenos Biosciences Reports P-II Trial Results on BEL512 for CRSwNP appeared first on PharmaShots.
