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The P-II (QUINTESSENTIAL) trial assessed arlocabtagene autoleucel (arlo-cel) in r/r MM pts, who were previously treated with an immunomodulatory inhibitor, a proteasome inhibitor, an anti-CD38 therapy & a BCMA-targeted therapy
The trial met its 1EP, showing improvement in ORR, & its key 2EP of CRR in the above-mentioned pts who had previously received ā„4L of therapy. Arlo-cel also achieved 2EPs of ORR and CRR after ā„3 prior lines of therapy
Arlo-cel (BMS-986393) is an autologous GPRC5D-directed CAR T-cell therapy designed to recognize & eliminate GPRC5D-expressing myeloma cells
Ref: Businesswire | Image: BMS | Press Release
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The post BMS Reports Topline P-II (QUINTESSENTIAL) Trial Data on Arlo-Cel for Heavily PretreatedĀ R/R Multiple Myeloma (MM) appeared first on PharmaShots.