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Evommune has entered into an exclusive license agreement with Hinova Pharmaceuticals for worldwide rights (ex-Greater China) to develop, manufacture & commercialize EVO570 (formerly HC118/HP570), an oral VAV1-directed molecular glue degrader
Evommune will pay $30M upfront ($20M cash + $10M in pre-funded warrants); Hinova is eligible for up to ~$1.1B in development, regulatory & commercial milestones, plus tiered royalties on net sales outside Greater China
EVO570 IND applications have been submitted in China & accepted in the US; a P-I trial assessing safety, PK & target engagement is expected to begin imminently, with a P-II in rheumatoid arthritis planned for 2027
Ref: Evommune | Image: Evommune & Hinova | Press Release
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The post Evommune Enters Exclusive License Agreement with Hinova for EVO570, an Oral VAV1 Molecular Glue Degrader appeared first on PharmaShots.
Evommune Enters Exclusive License Agreement with Hinova for EVO570, an Oral VAV1 Molecular Glue Degrader | PharmaVoice