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Jubilant Therapeutics has reported preliminary data from the P-I portion of the P-I/II (JBI-802-02) study of JBI-802 (oral dual LSD1/HDAC6 inhibitor) in pts with r/r or intolerant ET, PV & MDS/MPN with thrombocytosis, selected for an oral presentation at ASH 2026
As of Jun 30, 2026, all 8 pts on 15mg achieved >50% platelet reduction or normalization by Wk. 3 (median time to response: 15 days), with normalization maintained through 33, 44 & 46wks.; 7/11 pts with leukocytosis at 15mg achieved CHR
No DLTs were observed at 5, 7 or 15mg; further efficacy, safety & molecular data will be presented at ASH on Dec 14, 2026
Ref: PR Newswire | Image: Jubilant Therapeutics | Press Release
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The post Jubilant Therapeutics Reports Preliminary P-I Data of JBI-802 for Essential Thrombocythemia and Related MPNs appeared first on PharmaShots.
Jubilant Therapeutics Reports Preliminary P-I Data of JBI-802 for Essential Thrombocythemia and Related MPNs | PharmaVoice