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The US FDA has granted IND clearance to initiate P-I trial of PRT13722 in HR+/HER2− breast cancer, with patient enrollment expected to begin in Q4’26
The P-I study will assess PRT13722’s safety, tolerability, PK, PD & antitumor activity as monotx. & in combination with endocrine or targeted therapies in adults with locally advanced/metastatic HR+/HER2− breast cancer
PRT13722 is an oral KAT6A selective degrader
Ref: Globenewswire| Image: Prelude Therapeutics | Press Release
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Prelude Therapeutics Receives FDA IND Clearance for PRT13722 | PharmaVoice