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Suzhou Ribo Life Science & its subsidiary Ribocure Pharmaceuticals have submitted a P-I CTA in the EU for SR122, a dual GalNAc-conjugated siRNA, to treat dyslipidemia, incl. severe hypertriglyceridemia (sHTG) & mixed dyslipidemia
The randomized, placebo-controlled P-I trial will evaluate the safety, tolerability, PK & PD of SC SR122 in healthy participants, providing the first human evaluation of the dual-targeting approach
SR122 simultaneously targets ApoC3 & PCSK9 to address both triglyceride-rich lipoproteins & LDL-C; Ribo is also advancing P-II studies of its ApoC3-targeting siRNA, RBD5044, in Europe & China
Ref: PR Newswire | Image: Ribo | Press Release
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The post Ribo Submits CTA in the EU for P-I Trial of Dual-Targeting siRNA SR122 to Treat Dyslipidemia appeared first on PharmaShots.
Ribo Submits CTA in the EU for P-I Trial of Dual-Targeting siRNA SR122 to Treat Dyslipidemia | PharmaVoice